當(dāng)前位置:首頁 > 產(chǎn)品中心 > 抗體/抗原 > 一抗 > bsm-55559R腫瘤錯(cuò)配修復(fù)基因PMS2兔單克隆抗體
簡要描述:This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gen
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